AMG319 is primarily utilized in the field of medical research, particularly in the study of cancer therapies. It functions as a potent and selective inhibitor of the PI3K delta isoform, which plays a crucial role in cell growth and survival. By targeting this specific enzyme, AMG319 helps in investigating the pathways involved in tumor proliferation and immune response modulation. Its application is significant in preclinical studies aimed at understanding the mechanisms of various cancers, including hematologic malignancies, and in the development of targeted cancer treatments. Researchers also explore its potential in combination therapies to enhance the efficacy of existing cancer drugs.