1-Boc-4-(4-Nitrobenzyl)piperazine
98%
Reagent
Code: #145954
CAS Number
130636-61-2
blur_circular Chemical Specifications
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Molecular Information
Weight
321.37 g/mol
Formula
C₁₆H₂₃N₃O₄
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Registry Numbers
MDL Number
MFCD03407491
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) where protection of the piperazine nitrogen is required. The Boc (tert-butoxycarbonyl) group allows for selective protection during peptide coupling or alkylation reactions, while the 4-nitrobenzyl moiety can serve as a protecting group or be further modified through reduction to an amine for conjugation. Commonly employed in medicinal chemistry for constructing complex molecules, including kinase inhibitors and CNS-active agents. Its structure facilitates stepwise assembly in multi-step syntheses, improving yield and selectivity.
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