tert-Butyl 4-(2-bromoacetyl)piperazine-1-carboxylate
≥95%
Reagent
Code: #148233
CAS Number
112257-12-2
blur_circular Chemical Specifications
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Molecular Information
Weight
307.18 g/mol
Formula
C₁₁H₁₉BrN₂O₃
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Registry Numbers
MDL Number
MFCD16990579
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Physical Properties
Boiling Point
391.5±37.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the preparation of bioactive molecules and drug candidates. Its structure contains both a protected piperazine ring and a reactive bromoacetyl group, making it valuable for introducing piperazine-based moieties into larger molecules through nucleophilic substitution reactions. Commonly employed in the development of central nervous system agents, antimicrobials, and receptor modulators. The tert-butyl carbamate (Boc) protection allows for selective deprotection under mild acidic conditions, enabling stepwise synthesis in complex medicinal chemistry routes.
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