tert-Butyl 3-(trifluoromethyl)piperazine-1-carboxylate
97%
Reagent
Code: #148432
CAS Number
886779-69-7
blur_circular Chemical Specifications
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Molecular Information
Weight
254.25 g/mol
Formula
C₁₀H₁₇F₃N₂O₂
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Registry Numbers
MDL Number
MFCD08686626
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Physical Properties
Boiling Point
263.4±35.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules and drug candidates. Its piperazine core with trifluoromethyl and tert-butoxycarbonyl (Boc) groups makes it valuable in medicinal chemistry for constructing complex molecules with improved metabolic stability and binding affinity. Commonly employed in the preparation of kinase inhibitors, CNS-active agents, and antiviral compounds. The Boc group allows for easy protection of the amine during multi-step syntheses, while the trifluoromethyl moiety enhances lipophilicity and bioavailability. Also utilized in agrochemical research for designing novel active ingredients.
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