tert-Butyl 4-cyclohexyl-1-piperazinecarboxylate
97%
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description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system agents. Its structure, featuring a piperazine ring substituted with a cyclohexyl group and protected by a sterically hindered tert-butyl carbamate (Boc) group, supports the creation of bioactive molecules. The Boc group serves as a protecting group during synthesis, enhancing solubility in organic solvents and improving reaction control and yield, while also contributing to metabolic stability in final drug candidates. The cyclohexyl substituent adds lipophilicity, aiding in CNS penetration. Commonly employed in medicinal chemistry for constructing drug candidates targeting neurological disorders, including antidepressants and antipsychotics. Also utilized in research settings for scaffold modification and structure-activity relationship studies.
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