tert-Butyl 4-hydroxy-4-(trifluoromethyl)piperidine-1-carboxylate

≥98%

Reagent Code: #119589
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CAS Number 550371-74-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 269.26 g/mol
Formula C₁₁H₁₈F₃NO₃
badge Registry Numbers
MDL Number MFCD16990768
thermostat Physical Properties
Boiling Point 290.6±40.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, dry and sealed

description Product Description

This compound, tert-Butyl 4-hydroxy-4-(trifluoromethyl)piperidine-1-carboxylate, is primarily utilized in pharmaceutical research and development as a key intermediate in the synthesis of more complex molecules. Its structure features a piperidine ring substituted at the 4-position with both a hydroxy group and a trifluoromethyl group, with the nitrogen protected by a tert-butoxycarbonyl (Boc) group. This makes it valuable for creating compounds with potential biological activity. It is often employed in the design of drugs targeting the central nervous system, as the piperidine moiety is a common feature in many neuroactive substances. Additionally, the trifluoromethyl group enhances the metabolic stability and lipophilicity of the resulting compounds, improving their pharmacokinetic properties. The hydroxy group at the quaternary carbon provides opportunities for further functionalization. Researchers also explore its use in the development of agrochemicals, where its unique structure can contribute to the creation of novel pesticides or herbicides with enhanced efficacy.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿8,721.00
inventory 100mg
10-20 days ฿2,331.00
inventory 250mg
10-20 days ฿3,501.00

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