2-(((tert-Butyldimethylsilyl)oxy)methyl)piperidine
97%
Reagent
Code: #140935
CAS Number
135938-63-5
blur_circular Chemical Specifications
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Molecular Information
Weight
229.43 g/mol
Formula
C₁₂H₂₇NOSi
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Registry Numbers
MDL Number
MFCD22690318
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Physical Properties
Boiling Point
255.9±13.0 °C(Predicted)
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Storage & Handling
Density
0.866±0.06 g/cm3(Predicted)
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a protected intermediate in organic synthesis, particularly in the preparation of complex pharmaceuticals and natural products. The silyl ether group provides stability under a variety of reaction conditions while the piperidine ring can act as a structural scaffold. Commonly employed in multi-step syntheses where selective deprotection is required, enabling controlled functionalization. Its main utility lies in masking hydroxyl groups during peptide or alkaloid synthesis, allowing reactions to proceed at other reactive sites without interference. Widely applied in medicinal chemistry for building nitrogen-containing heterocycles with high regio- and stereocontrol.
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