PP58 is primarily utilized in biochemical research as a selective inhibitor of protein kinase C (PKC) isoforms. Its application is significant in studying cellular signaling pathways, particularly those involving PKC, which plays a crucial role in various physiological processes, including cell proliferation, differentiation, and apoptosis. Researchers employ PP58 to investigate the specific functions of PKC isoforms in different cellular contexts, aiding in the understanding of diseases where PKC signaling is dysregulated, such as cancer, diabetes, and cardiovascular disorders. Additionally, PP58 is used in pharmacological studies to explore potential therapeutic strategies targeting PKC-related pathways.