AEB071 is primarily utilized in the field of medical research, particularly in the study of immune system modulation. It functions as a potent inhibitor of protein kinase C (PKC), which plays a critical role in T-cell activation and signaling pathways. By inhibiting PKC, it is explored for its potential in preventing organ transplant rejection, as it can suppress the immune response that leads to graft rejection. Additionally, it is being investigated for its efficacy in treating autoimmune diseases and certain types of cancers where PKC signaling is dysregulated. Its application in clinical trials has shown promise in improving patient outcomes by targeting specific cellular mechanisms involved in disease progression.