A 419259
98%
science Other reagents with same CAS 364042-47-7
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description Product Description
This compound is primarily utilized in biochemical research as a potent and selective inhibitor of spleen tyrosine kinase (Syk). It is particularly effective in studying the role of Syk in cellular signaling pathways, especially in immune cells like B cells, mast cells, and basophils, aiding in the understanding of processes such as B cell receptor signaling, immune responses, inflammation, and allergic reactions. Researchers employ it to investigate the therapeutic potential of Syk inhibition in diseases including rheumatoid arthritis, asthma, allergies, and certain cancers. Its high specificity (>1000-fold over other kinases) makes it a valuable tool for elucidating the mechanisms of Syk-related pathways in both normal and pathological states.
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