CFI-400945 fumarate
98%
Reagent
Code: #108123
CAS Number
1616420-30-4
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
650.72 g/mol
Formula
C₃₇H₃₈N₄O₇
inventory_2
Storage & Handling
Storage
-20°C, airtight, dry
description Product Description
CFI-400945 fumarate is primarily used in cancer research due to its role as a selective inhibitor of Polo-like kinase 4 (PLK4). PLK4 is a key regulator of centriole duplication, and its overexpression is often linked to tumorigenesis. By inhibiting PLK4, this compound disrupts centriole formation, leading to mitotic defects and ultimately inducing cancer cell death. It is particularly studied in the context of solid tumors and hematological malignancies. Researchers utilize CFI-400945 fumarate to explore its potential as a therapeutic agent, focusing on its ability to target cancer cells while sparing normal cells. Additionally, it serves as a valuable tool in understanding the molecular mechanisms of PLK4 in cell cycle regulation and cancer progression.
shopping_cart Available Sizes & Pricing
CFI-400945 fumarate
CFI-400945 fumarate is primarily used in cancer research due to its role as a selective inhibitor of Polo-like kinase 4 (PLK4). PLK4 is a key regulator of centriole duplication, and its overexpression is often linked to tumorigenesis. By inhibiting PLK4, this compound disrupts centriole formation, leading to mitotic defects and ultimately inducing cancer cell death. It is particularly studied in the context of solid tumors and hematological malignancies. Researchers utilize CFI-400945 fumarate to explore its potential as a therapeutic agent, focusing on its ability to target cancer cells while sparing normal cells. Additionally, it serves as a valuable tool in understanding the molecular mechanisms of PLK4 in cell cycle regulation and cancer progression.
Mechanism | - |
Appearance | - |
Longevity | - |
Strength | - |
Storage | - |
Shelf Life | - |
Allergen(s) | - |
Dosage (Range) | - |
Recommended Dosage | - |
Dosage (Per Day) | - |
Recommended Dosage (Per Day) | - |
Mix Method | - |
Heat Resistance | - |
Stable in pH range | - |
Solubility | - |
Product Types | - |
INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
Total
฿0.00
THB