2,2',4,6,6'-Pentachlorobiphenyl is primarily used in industrial applications, particularly as a component in dielectric fluids for electrical equipment like transformers and capacitors. Its chemical stability makes it suitable for insulating purposes, ensuring efficient performance under high voltage conditions. Additionally, it has been utilized in heat transfer systems due to its thermal stability. However, its use has significantly declined due to environmental and health concerns, as it is classified as a persistent organic pollutant (POP). In research, it serves as a reference compound in studies focusing on the environmental impact and toxicity of polychlorinated biphenyls (PCBs). Efforts are now directed toward monitoring its presence in ecosystems and developing methods for its safe disposal or remediation.