tert-Butyl 3-(2-(2-(methylamino)ethoxy)ethoxy)propanoate
97%
Reagent
Code: #63032
CAS Number
1807521-04-5
science Other reagents with same CAS 1807521-04-5
blur_circular Chemical Specifications
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Molecular Information
Weight
247.33 g/mol
Formula
C₁₂H₂₅NO₄
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Registry Numbers
MDL Number
MFCD28155207
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Physical Properties
Boiling Point
315.5±22.0 °C(Predicted)
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Storage & Handling
Density
0.982±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
tert-Butyl 3-(2-(2-(methylamino)ethoxy)ethoxy)propanoate is a specialty chemical intermediate featuring a tert-butyl ester and a diethylene glycol linker with a terminal N-methylamine. It is used in pharmaceutical research for synthesizing complex APIs, linkers in antibody-drug conjugates (ADCs), PROTACs, and prodrugs. The hydrophilic PEG-like chain enhances solubility and drug delivery, while the amine enables conjugation via reductive amination or acylation, and the ester provides selective deprotection under acidic conditions.
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