NS3623 is primarily used in research settings to study ion channels, particularly potassium channels. It acts as a potent activator of these channels, making it valuable for understanding their role in cellular processes. This compound is often employed in electrophysiological studies to investigate the mechanisms of channel gating and ion flow. Additionally, NS3623 is utilized in exploring potential therapeutic applications, such as targeting potassium channels in conditions like cardiac arrhythmias or neurological disorders. Its ability to modulate ion channel activity also makes it a useful tool in drug discovery and development, helping to identify new treatments for diseases linked to ion channel dysfunction.