NS-1619 is primarily used as a research tool in scientific studies, particularly in the field of pharmacology and physiology. It is known for its ability to activate large-conductance calcium-activated potassium (BK) channels, which play a crucial role in regulating cellular excitability and vascular tone. Researchers utilize NS-1619 to investigate the physiological and pathological roles of BK channels in various tissues, including smooth muscle, neurons, and endothelial cells. Its application extends to studying potential therapeutic effects in conditions such as hypertension, stroke, and other cardiovascular diseases. Additionally, NS-1619 is employed in experimental models to explore its neuroprotective properties and its impact on cellular signaling pathways.