GW 6471 is primarily utilized in research settings as a selective antagonist for the peroxisome proliferator-activated receptor beta/delta (PPARβ/δ). It is widely used in studies to investigate the role of PPARβ/δ in various biological processes, including lipid metabolism, inflammation, and cellular differentiation. Researchers employ GW 6471 to inhibit PPARβ/δ activity, helping to elucidate its function in metabolic disorders, cardiovascular diseases, and cancer. Additionally, it serves as a valuable tool in understanding the molecular mechanisms underlying PPARβ/δ signaling pathways and its potential as a therapeutic target. Its application is largely confined to preclinical studies, contributing to advancements in pharmacology and molecular biology.