L-663536 is primarily utilized in research settings to study its effects on specific biochemical pathways. It acts as a selective inhibitor of the enzyme 5-lipoxygenase (5-LOX), which plays a key role in the production of leukotrienes involved in inflammation and conditions such as asthma. This makes it valuable for understanding cellular processes and signaling mechanisms related to immune response modulation. Researchers employ it to investigate potential therapeutic applications, particularly in areas like inflammation, arthritis, and neurological diseases, where it can reduce inflammation and tissue damage. Its application extends to preclinical studies, evaluating efficacy and safety profiles in various disease models.