PROTAC MDM2 Degrader-2 is primarily utilized in biomedical research, particularly in the field of targeted protein degradation. Its application is significant in studying cancer biology, as it is designed to degrade MDM2, a protein that negatively regulates the tumor suppressor p53. By inducing the degradation of MDM2, this compound helps to restore p53 activity, which can lead to the suppression of tumor growth and the promotion of cancer cell death. Researchers employ this chemical tool to investigate the therapeutic potential of MDM2 inhibition in various cancer models, aiding in the development of novel cancer treatments. Additionally, it serves as a valuable probe to explore the mechanisms of PROTAC technology and its efficacy in degrading specific disease-related proteins.