PROTAC PD-1/PD-L1 degrader-1
98%
Reagent
Code: #106405
CAS Number
2447066-37-5
blur_circular Chemical Specifications
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Molecular Information
Weight
1076.59 g/mol
Formula
C₅₉H₅₈ClN₇O₁₁
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Storage & Handling
Storage
-20°C
description Product Description
This chemical is specifically designed to target and degrade PD-1 and PD-L1 proteins, which are key players in immune checkpoint pathways. By degrading these proteins, it helps to enhance the immune system's ability to recognize and attack cancer cells. This makes it a promising candidate for cancer immunotherapy, particularly in cases where tumors evade immune detection through the PD-1/PD-L1 pathway. Its application could lead to more effective treatments for various types of cancers, including melanoma, lung cancer, and others that exploit this immune evasion mechanism. Additionally, it offers a novel approach compared to traditional inhibitors, as it directly removes the target proteins rather than just blocking their function.
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