(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2
95%
Reagent
Code: #106007
CAS Number
2409538-69-6
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Molecular Information
Weight
633.80 g/mol
Formula
C₃₁H₄₇N₅O₇S
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). It functions as a linker molecule that connects an E3 ligase ligand to a target protein ligand, enabling the selective degradation of specific proteins within cells. Its structure, featuring a PEG3 spacer, enhances solubility and flexibility, facilitating efficient interaction between the E3 ligase and the target protein. This makes it valuable in research focused on understanding disease mechanisms and developing therapeutic strategies, especially in oncology and neurodegenerative disorders. Additionally, its application extends to chemical biology studies where precise control over protein levels is required to investigate cellular processes.
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(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). It functions as a linker molecule that connects an E3 ligase ligand to a target protein ligand, enabling the selective degradation of specific proteins within cells. Its structure, featuring a PEG3 spacer, enhances solubility and flexibility, facilitating efficient interaction between the E3 ligase and the target protein. This makes it valuable in research focused on understanding disease mechanisms and developing therapeutic strategies, especially in oncology and neurodegenerative disorders. Additionally, its application extends to chemical biology studies where precise control over protein levels is required to investigate cellular processes.
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