(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc

97%

Reagent Code: #106008
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CAS Number 2409007-40-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 723.88 g/mol
Formula C₃₇H₄₉N₅O₈S
inventory_2 Storage & Handling
Storage 2-8°C, dry, sealed

description Product Description

Used in the field of targeted protein degradation, this compound is a key component in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the selective degradation of specific proteins by linking a target protein to an E3 ubiquitin ligase, leading to its ubiquitination and subsequent proteasomal degradation. This mechanism is particularly valuable in drug discovery, especially for targeting undruggable proteins in diseases like cancer, neurodegenerative disorders, and autoimmune conditions. Its structure, featuring a Boc-protected amine and PEG linker, ensures stability and efficient cellular uptake, making it a versatile tool in chemical biology and therapeutic research.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days €830.37
(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc
Used in the field of targeted protein degradation, this compound is a key component in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the selective degradation of specific proteins by linking a target protein to an E3 ubiquitin ligase, leading to its ubiquitination and subsequent proteasomal degradation. This mechanism is particularly valuable in drug discovery, especially for targeting undruggable proteins in diseases like cancer, neurodegenerative disorders, and autoimmune conditions. Its structure, featuring a Boc-protected amine and PEG linker, ensures stability and efficient cellular uptake, making it a versatile tool in chemical biology and therapeutic research.
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