(S,R,S)-AHPC-PEG6-C4-Cl
≥96%
Reagent
Code: #106013
CAS Number
1835705-59-3
blur_circular Chemical Specifications
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Molecular Information
Weight
827.47 g/mol
Formula
C₄₀H₆₃ClN₄O₁₀S
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Storage & Handling
Storage
2-8℃
description Product Description
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). It serves as a key linker molecule, connecting the E3 ligase ligand to the target protein ligand, enabling the selective degradation of specific proteins within cells. Its PEG6 spacer enhances solubility and flexibility, improving the efficiency of the PROTAC molecule in cellular environments. The compound is also employed in research focused on understanding protein-protein interactions and signaling pathways, aiding in the discovery of novel therapeutic targets for diseases such as cancer and neurodegenerative disorders. Additionally, its application extends to chemical biology studies, where it is used to explore the mechanisms of ubiquitin-proteasome system-mediated protein degradation.
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(S,R,S)-AHPC-PEG6-C4-Cl
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). It serves as a key linker molecule, connecting the E3 ligase ligand to the target protein ligand, enabling the selective degradation of specific proteins within cells. Its PEG6 spacer enhances solubility and flexibility, improving the efficiency of the PROTAC molecule in cellular environments. The compound is also employed in research focused on understanding protein-protein interactions and signaling pathways, aiding in the discovery of novel therapeutic targets for diseases such as cancer and neurodegenerative disorders. Additionally, its application extends to chemical biology studies, where it is used to explore the mechanisms of ubiquitin-proteasome system-mediated protein degradation.
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