Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc
≥95%
Reagent
Code: #109361
CAS Number
2435720-04-8
blur_circular Chemical Specifications
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Molecular Information
Weight
631.67 g/mol
Formula
C₃₀H₄₁N₅O₁₀
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is primarily utilized in the development of targeted cancer therapies, particularly in the field of proteolysis-targeting chimeras (PROTACs). Its structure allows it to act as a linker molecule, connecting a target protein-binding moiety (such as pomalidomide) to an E3 ubiquitin ligase-recruiting group. This facilitates the degradation of specific disease-causing proteins, offering a promising approach for treating cancers and other protein-related disorders. Additionally, the PEG2 spacer enhances solubility and bioavailability, while the Boc group provides protection during synthetic processes, ensuring stability and efficiency in drug development.
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Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is primarily utilized in the development of targeted cancer therapies, particularly in the field of proteolysis-targeting chimeras (PROTACs). Its structure allows it to act as a linker molecule, connecting a target protein-binding moiety (such as pomalidomide) to an E3 ubiquitin ligase-recruiting group. This facilitates the degradation of specific disease-causing proteins, offering a promising approach for treating cancers and other protein-related disorders. Additionally, the PEG2 spacer enhances solubility and bioavailability, while the Boc group provides protection during synthetic processes, ensuring stability and efficiency in drug development.
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