2-(2,6-Dioxopiperidin-3-yl)-5-methylisoindoline-1,3-dione

98%

Reagent Code: #128882
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CAS Number 40313-92-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 272.26 g/mol
Formula C₁₄H₁₂N₂O₄
badge Registry Numbers
MDL Number MFCD30290642
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Widely used in pharmaceutical research, this compound serves as a key intermediate in the synthesis of immunomodulatory drugs. It is particularly valuable in the development of targeted protein degraders, such as cereblon E3 ligase modulators, which are used in cancer therapies. Its structure enables selective binding to cereblon, facilitating the degradation of disease-causing proteins. Due to this mechanism, it plays a critical role in the design of treatments for hematological malignancies, including multiple myeloma and myelodysplastic syndromes. It is also explored for anti-inflammatory and anti-angiogenic applications in preclinical studies.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,230.00
inventory 1g
10-20 days ฿6,000.00
inventory 5g
10-20 days ฿21,000.00

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