3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride
98%
Reagent
Code: #129807
CAS Number
2259851-38-0
blur_circular Chemical Specifications
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Molecular Information
Weight
323.82 g/mol
Formula
C₁₆H₂₂ClN₃O₂
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of analogs related to thalidomide and lenalidomide. It exhibits potential in targeting E3 ubiquitin ligase complexes, making it valuable in the design of proteolysis-targeting chimeras (PROTACs) for cancer therapy. Its structure supports binding to cereblon, a protein involved in protein degradation pathways, enabling selective degradation of disease-causing proteins. Also investigated for anti-inflammatory and anti-angiogenic properties in preclinical studies.
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