5-(Bromomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

98%

Reagent Code: #130189
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CAS Number 1312023-72-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 351.15 g/mol
Formula C₁₄H₁₁BrN₂O₄
badge Registry Numbers
MDL Number MFCD34601661
thermostat Physical Properties
Boiling Point 583.1±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.745±0.06 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its bromomethyl functional group allows for efficient conjugation to other molecules, enabling the development of PROTACs (proteolysis-targeting chimeras) that direct specific proteins for degradation. This compound is valuable in oncology and immunology drug discovery due to its role in enhancing selectivity and potency of therapeutic agents. It is also employed in the preparation of analogs for structure-activity relationship studies.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,430.00
inventory 1g
10-20 days ฿20,250.00
inventory 250mg
10-20 days ฿7,510.00

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