Used in pharmaceutical research as a key building block for designing drug candidates, particularly in the development of proteolysis-targeting chimeras (PROTACs) and other targeted therapies. Its rigid bicyclic structure enhances metabolic stability and improves binding selectivity, making it valuable in optimizing pharmacokinetic properties. Commonly employed to introduce steric hindrance and reduce off-target effects in small molecule drugs. Also utilized in medicinal chemistry for scaffold diversification due to its unique three-dimensional architecture and favorable solubility profile when salt forms are used.