tert-Butyl 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetate
98%
Reagent
Code: #131076
CAS Number
1950635-36-5
blur_circular Chemical Specifications
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Molecular Information
Weight
388.37 g/mol
Formula
C₁₉H₂₀N₂O₇
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Registry Numbers
MDL Number
MFCD32643096
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Storage & Handling
Storage
Room temperature, seal, inert gas
description Product Description
Used as an intermediate in the synthesis of targeted protein degradation therapeutics, particularly in the development of PROTACs (proteolysis-targeting chimeras). It serves to link E3 ligase ligands to target protein binders, enabling the degradation of disease-causing proteins. Its structure supports improved solubility and stability in cellular environments, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly applied in oncology research due to its role in degrading proteins involved in cancer progression.
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