4-Hydroxy-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
97%
Reagent
Code: #131607
CAS Number
2244568-06-5
blur_circular Chemical Specifications
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Molecular Information
Weight
288.26 g/mol
Formula
C₁₄H₁₂N₂O₅
thermostat
Physical Properties
Boiling Point
530.1±45.0 °C(Predicted)
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Storage & Handling
Density
1.556±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, inert gas
description Product Description
Widely used in biomedical research for its immunomodulatory and anti-inflammatory properties. Acts as a cereblon E3 ligase modulator, making it valuable in the development of targeted protein degradation therapies, especially in oncology. Commonly employed in studies related to multiple myeloma and other hematological cancers due to its ability to inhibit the proliferation of malignant cells. Also utilized in the synthesis of PROTACs (proteolysis-targeting chimeras) to selectively degrade disease-causing proteins. Its structure serves as a scaffold in designing novel derivatives with enhanced potency and selectivity.
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