1-(2,6-Dioxopiperidin-3-yl)-5-oxopyrrolidine-3-carboxylic acid

80%

Reagent Code: #131620
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CAS Number 1498191-33-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 240.21 g/mol
Formula C₁₀H₁₂N₂O₅
badge Registry Numbers
MDL Number MFCD23167038
thermostat Physical Properties
Boiling Point 613.6±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.523±0.06 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used primarily in pharmaceutical research as a key intermediate in the synthesis of immunomodulatory drugs, particularly those related to thalidomide analogs. It plays a critical role in the development of targeted protein degraders such as PROTACs, where it serves as a ligand for cereblon (CRBN), a component of the E3 ubiquitin ligase complex. By recruiting cereblon, this compound enables the selective degradation of disease-related proteins, making it valuable in oncology and inflammatory disease research. Its structure allows for chemical modifications that enhance binding affinity, selectivity, and pharmacokinetic properties in drug candidates.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,800.00
inventory 250mg
10-20 days ฿9,850.00
inventory 1g
10-20 days ฿26,600.00

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