5-(Aminomethyl)isoindoline-1,3-dione hydrochloride
97%
Reagent
Code: #131640
CAS Number
2682112-48-5
blur_circular Chemical Specifications
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Molecular Information
Weight
212.63 g/mol
Formula
C₉H₉ClN₂O₂
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Storage & Handling
Storage
Room temperature, seal, inert gas
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structure allows for effective linker incorporation between an E3 ligase ligand and a target protein binder, enabling targeted protein degradation. The hydrochloride salt form enhances solubility and stability, making it suitable for use in aqueous reaction conditions. It is also employed in the preparation of bioconjugates and labeled compounds for biochemical assays and drug discovery research.
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