2-Azido-N-(1R,2S)-1-[4-(6-cyano-3-pyridinyl)phenyl]-3-fluoro-1-hydroxy-2-propanylacetamide
95%
Reagent
Code: #137531
CAS Number
605650-58-6
blur_circular Chemical Specifications
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Molecular Information
Weight
354.34 g/mol
Formula
C₁₇H₁₅FN₆O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of selective kinase inhibitors, particularly for targeted cancer therapies. Its azide and cyano functional groups enable click chemistry reactions, facilitating rapid compound diversification and labeling for biochemical assays. The fluorinated hydroxypropanyl acetamide structure enhances binding specificity to certain protein targets, making it valuable in the development of proteolysis-targeting chimeras (PROTACs) and other targeted degradation agents. Commonly employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved potency and metabolic stability.
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