2-(2-(2-(4-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide
95%
Reagent
Code: #139040
CAS Number
2231744-29-7
blur_circular Chemical Specifications
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Molecular Information
Weight
787.8200000000001 g/mol
Formula
C₄₁H₄₁N₉O₈
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Storage & Handling
Storage
-20°C
description Product Description
Used as a targeted protein degrader in cancer research, particularly as a cereblon E3 ligase modulator. It functions by binding to specific disease-causing proteins and promoting their ubiquitination and subsequent degradation by the cell's proteasome system.
This compound is designed to target oncogenic or dysregulated proteins involved in hematological malignancies and solid tumors, making it a valuable tool in developing therapies for conditions like multiple myeloma and other cancers.
Its structure enables enhanced selectivity and cellular permeability, supporting its use in preclinical studies to evaluate efficacy, pharmacokinetics, and mechanism of action in protein degradation pathways.
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