3-(5-bromo-4-chloro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

97%

Reagent Code: #140679
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CAS Number 2474671-24-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 357.59 g/mol
Formula C₁₃H₁₀BrClN₂O₃
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used primarily as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of immunomodulatory drugs that selectively tag disease-causing proteins for degradation. Its structure enables high binding affinity to cereblon, making it valuable in oncology research, especially in therapies for hematological cancers such as multiple myeloma and myelodysplastic syndromes. Also utilized in the design of PROTACs (proteolysis-targeting chimeras) due to its ability to recruit E3 ubiquitin ligase complexes.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿3,200.00
inventory 25mg
10-20 days ฿9,600.00
inventory bulk
10-20 days ฿0.00

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