3-(5-bromo-6-methoxy-1-oxo-isoindolin-2-yl)piperidine-2,6-dione

99%

Reagent Code: #140686
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CAS Number 2438240-01-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 353.17 g/mol
Formula C₁₄H₁₃BrN₂O₄
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used in pharmaceutical research as a key intermediate for synthesizing targeted protein degraders, particularly cereblon (CRBN)-based PROTACs (proteolysis-targeting chimeras). Its structure enables selective binding to cereblon E3 ubiquitin ligase, facilitating the degradation of disease-related proteins. This compound is valuable in developing treatments for cancers and other conditions involving dysregulated protein expression. It is also employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of novel therapeutics.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿23,850.00
inventory 250mg
10-20 days ฿47,700.00
inventory 1g
10-20 days ฿143,200.00
inventory bulk
10-20 days ฿0.00

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