3-(7-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
99%
Reagent
Code: #148840
CAS Number
2229976-08-1
blur_circular Chemical Specifications
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Molecular Information
Weight
323.15 g/mol
Formula
C₁₃H₁₁BrN₂O₃
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Storage & Handling
Storage
2-8℃
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo substituent allows further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Grey solid |
| Purity (%) | 98.5-100% |
| NMR | Conforms to Structure |
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