3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
98%
Reagent
Code: #149953
CAS Number
2304513-76-4
blur_circular Chemical Specifications
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Molecular Information
Weight
323.14 g/mol
Formula
C₁₃H₁₁BrN₂O₃
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Registry Numbers
MDL Number
MFCD32667217
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Storage & Handling
Storage
Room temperature, airtight, dry
description Product Description
Used as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon E3 ligase modulators. It plays a critical role in targeted protein degradation therapies, including PROTACs (proteolysis-targeting chimeras), which are emerging as powerful tools for treating cancers and other diseases by selectively degrading disease-causing proteins. Its structure enables effective binding to cereblon, making it valuable in designing molecules with enhanced selectivity and potency in oncology research.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Gray to Gray-Purple Powder |
| Purity | 97.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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