3-(5-Bromo-7-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
95%
Reagent
Code: #153194
CAS Number
2438240-68-5
blur_circular Chemical Specifications
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Molecular Information
Weight
341.13 g/mol
Formula
C₁₃H₁₀BrFN₂O₃
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, facilitating the degradation of disease-causing proteins. This makes it valuable in developing treatments for cancers such as multiple myeloma and other hematological malignancies. Also explored in the design of PROTACs (proteolysis-targeting chimeras) for its ability to link with target protein ligands, enhancing specificity and efficacy in drug development.
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