4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbohydrazide
≥95%
Reagent
Code: #167656
CAS Number
181148-00-5
science Other reagents with same CAS 181148-00-5
blur_circular Chemical Specifications
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Molecular Information
Weight
251.28 g/mol
Formula
C₁₂H₁₇N₃O₃
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Registry Numbers
MDL Number
MFCD01863409
thermostat
Physical Properties
Melting Point
213-215 °C
Boiling Point
492.1±14.0 °C(Predicted)
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Storage & Handling
Storage
Room temperature, sealed
description Product Description
Used as a key intermediate in the synthesis of bioactive molecules and pharmaceuticals, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structure allows for conjugation between E3 ligase ligands and target protein binders, facilitating targeted protein degradation. Commonly employed in medicinal chemistry research for designing novel therapeutics in oncology and neurodegenerative diseases. Also utilized in polymer chemistry as a crosslinking agent due to its ability to form stable amide and imide bonds. Shows utility in bioconjugation techniques for diagnostic and imaging agents.
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