2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-5-carboxylic acid

98%

Reagent Code: #176381
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CAS Number 1216805-11-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 302.24 g/mol
Formula C₁₄H₁₀N₂O₆
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used primarily in pharmaceutical research as a key intermediate in the synthesis of immunomodulatory drugs, particularly those related to thalidomide analogs. It plays a critical role in the development of targeted protein degraders such as PROTACs, where it serves as a ligand for cereblon (CRBN), an E3 ubiquitin ligase. By binding to cereblon, this compound enables the selective degradation of disease-related proteins, making it valuable in oncology and inflammatory disease research. Its carboxylic acid functional group allows for easy conjugation to other molecules, facilitating the creation of complex drug architectures for studying cellular pathways and developing novel therapeutics.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,300.00
inventory 1g
10-20 days ฿4,910.00
inventory 5g
10-20 days ฿17,130.00
inventory 10g
10-20 days ฿32,650.00

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