Used primarily in biochemical and pharmaceutical research as a potent inhibitor of matrix metalloproteinases (MMPs), particularly MMP-2 and MMP-9. These enzymes are involved in the degradation of extracellular matrix components and play key roles in cancer metastasis, inflammation, and tissue remodeling. The compound’s hydroxamic acid-like structure enables strong chelation of zinc ions at the active site of MMPs, making it an effective scaffold in the development of anticancer and anti-inflammatory agents. It is also employed in studies related to angiogenesis and tumor progression due to its ability to modulate cell invasion and migration. Its (Z)-configuration is critical for optimal binding and inhibitory activity.