Ac-WEHD-AFC

98%

Reagent Code: #107488
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CAS Number 210344-99-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 838.8 g/mol
Formula C₃₈H₃₇F₃N₈O₁₁
inventory_2 Storage & Handling
Storage -20°C, airtight, dry

description Product Description

This compound is primarily used in biochemical research as a fluorogenic substrate for caspase-1 and other related caspases. It is instrumental in studying apoptosis and inflammation processes, as caspase-1 plays a critical role in these pathways. Researchers utilize it to measure caspase activity in vitro, enabling the assessment of enzyme kinetics and inhibitor screening. The AFC (7-amino-4-trifluoromethylcoumarin) moiety is cleaved upon caspase activation, releasing a fluorescent signal that can be quantified to determine enzymatic activity. This makes it a valuable tool in drug discovery and the study of cellular mechanisms underlying diseases like cancer and autoimmune disorders.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿36,792.00

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