1-Boc-4,4-dimethyl-L-proline Methyl Ester

95%

Reagent Code: #104304
fingerprint
CAS Number 138423-86-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 257.33 g/mol
Formula C₁₃H₂₃NO₄
badge Registry Numbers
MDL Number MFCD18914400
thermostat Physical Properties
Boiling Point 305.4±35.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.059±0.06 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

This compound, 1-Boc-4,4-dimethyl-L-proline methyl ester, is primarily used in organic synthesis, particularly in peptide chemistry. It serves as a dually protected form of 4,4-dimethyl-L-proline, where the Boc (tert-butoxycarbonyl) group safeguards the amine functionality and the methyl ester protects the carboxylic acid during reactions. This allows for selective modification of other parts of the molecule without affecting the amine or carboxylic groups. The 4,4-dimethyl substitution at the pyrrolidine ring provides steric bulk, which can constrain peptide conformations and enhance stability in peptidomimetics. It is commonly employed in the synthesis of complex peptides and peptidomimetics, which are crucial in drug discovery and development. Additionally, its stability and ease of deprotection make it a valuable intermediate in the preparation of biologically active compounds, including pharmaceuticals targeting various diseases.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿15,750.00
inventory 100mg
10-20 days ฿9,000.00
inventory 1g
10-20 days ฿40,500.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB