This compound is primarily utilized in peptide synthesis, where it serves as a protected form of histidine. The BOC (tert-butyloxycarbonyl) and 3-BOM (benzyloxymethyl) groups protect the amino and imidazole side chain, respectively, preventing unwanted reactions during the peptide assembly process. The methyl ester (OME) group protects the carboxyl functionality. This protection strategy ensures selective deprotection and coupling steps, enabling the precise construction of complex peptides. It is particularly valuable in the synthesis of peptides for pharmaceutical research, where histidine residues play critical roles in biological activity. The hydrochloride form enhances solubility, facilitating its use in various organic solvents during synthesis.