Fmoc-L-β-Homoasparagine
95%
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description Product Description
Fmoc-L-β-Homoasparagine is a protected derivative of the non-proteinogenic amino acid L-β-Homoasparagine, used as a building block in peptide synthesis. The Fmoc (9-fluorenylmethyloxycarbonyl) protecting group shields the α-amino group, enabling controlled incorporation into growing peptide chains during solid-phase peptide synthesis (SPPS) without unwanted side reactions. This specificity allows the construction of complex peptides containing β-homoasparagine residues, which can alter peptide conformation or mimic post-translational modifications. It is widely applied in pharmaceutical development for creating therapeutic peptides with enhanced stability and bioavailability, as well as in biochemical research to investigate protein interactions, enzyme substrates, and signaling pathways. The Fmoc group's stability under synthesis conditions and facile removal with mild bases like piperidine make it a preferred choice for efficient, high-purity peptide production.
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