Fmoc-Trp(Boc)-OH

97.0%

Reagent Code: #105105
label
Alias Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-Butoxycarbonyl-L-Tryptophan, Fmoc-L-Tryptophan(Boc)-OH
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CAS Number 143824-78-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 526.58 g/mol
Formula C₃₁H₃₀N₂O₆
badge Registry Numbers
MDL Number MFCD00153366
inventory_2 Storage & Handling
Storage 2~8°C

description Product Description

This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid building block, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality, and the Boc (tert-butyloxycarbonyl) group protects the indole side chain of tryptophan. Its primary application is in the production of peptides for research and pharmaceutical purposes, ensuring precise and controlled assembly of peptide chains. It is especially valuable in synthesizing peptides containing tryptophan residues, which are prone to oxidation or side reactions during synthesis. The compound is also utilized in the development of peptide-based drugs, diagnostics, and biochemical tools, contributing to advancements in medicinal chemistry and biotechnology.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance White to orange to green powder to crystal
Purity (HPLC) 97-100
Melting Point 90-100
Infrared Spectrum Conforms To Structure
Specific Rotation [α]20/D (C=1, DMF) -18.0 to -22.0°

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25g
10-20 days ฿4,480.00
inventory 1g
10-20 days ฿390.00
inventory 5g
10-20 days ฿1,280.00
inventory 100g
10-20 days ฿16,280.00
Fmoc-Trp(Boc)-OH
This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid building block, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality, and the Boc (tert-butyloxycarbonyl) group protects the indole side chain of tryptophan. Its primary application is in the production of peptides for research and pharmaceutical purposes, ensuring precise and controlled assembly of peptide chains. It is especially valuable in synthesizing peptides containing tryptophan residues, which are prone to oxidation or side reactions during synthesis. The compound is also utilized in the development of peptide-based drugs, diagnostics, and biochemical tools, contributing to advancements in medicinal chemistry and biotechnology.
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