Fmoc-Ser(Trt)-OH
98%
Reagent
Code: #105132
Alias
Fmoc-O-trityl-L-serine ; N-(9-fluorenylmethoxycarbonyl)-O-trityl-L-serine
CAS Number
111061-56-4
blur_circular Chemical Specifications
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Molecular Information
Weight
569.65 g/mol
Formula
C₃₇H₃₁NO₅
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Registry Numbers
MDL Number
MFCD00153364
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Physical Properties
Melting Point
200-210 °C (dec.)
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Storage & Handling
Storage
2~8°C
description Product Description
Used in peptide synthesis as a protecting group for serine, ensuring selective reactions during the assembly of peptide chains. It is particularly valuable in solid-phase peptide synthesis (SPPS) where the Fmoc group provides temporary protection, while the Trt group safeguards the hydroxyl side chain of serine. This allows for precise control over the peptide-building process, minimizing unwanted side reactions. It is widely applied in the production of therapeutic peptides, research peptides, and biochemical studies. The compound’s stability and compatibility with standard SPPS protocols make it a reliable choice for synthesizing complex peptides with high purity and yield.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Melting Point | 197-199 |
Purity (HPLC) | 98-100 |
Specific Rotation [A]20/D (C = 1% DMF) | 7-9 |
Appearance | White To Light Yellow Powder |
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Fmoc-Ser(Trt)-OH
Used in peptide synthesis as a protecting group for serine, ensuring selective reactions during the assembly of peptide chains. It is particularly valuable in solid-phase peptide synthesis (SPPS) where the Fmoc group provides temporary protection, while the Trt group safeguards the hydroxyl side chain of serine. This allows for precise control over the peptide-building process, minimizing unwanted side reactions. It is widely applied in the production of therapeutic peptides, research peptides, and biochemical studies. The compound’s stability and compatibility with standard SPPS protocols make it a reliable choice for synthesizing complex peptides with high purity and yield.
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