Fmoc-Thr(tBu)-OH
98%
Reagent
Code: #105136
Alias
Fmoc-O-tert-butyl-L-threonine ;Fmoc-O-tert-butyl-L-threonine
CAS Number
71989-35-0
blur_circular Chemical Specifications
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Molecular Information
Weight
397.46 g/mol
Formula
C₂₃H₂₇NO₅
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Registry Numbers
EC Number
276-261-1
MDL Number
MFCD00077075
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Physical Properties
Melting Point
131-134 °C
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Storage & Handling
Storage
2~8℃
description Product Description
Fmoc-Thr(tBu)-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a building block for introducing threonine residues into peptides while protecting the hydroxyl group with a tert-butyl (tBu) group. The Fmoc (9-fluorenylmethoxycarbonyl) group provides temporary protection for the amino group, allowing for selective deprotection during the synthesis process. This compound is essential in the production of complex peptides and proteins for research, pharmaceuticals, and biotechnology applications. Its stability and compatibility with Fmoc-based synthesis protocols make it a valuable tool in the development of therapeutic peptides, vaccines, and diagnostic agents.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Purity (HPLC) | 98-100 |
Specific Rotation [A]20/D (C=1 in Ethyl Acetate) | 14-17°C |
Acetate | 14-17° |
Melting Point | 131-135 |
Water (Karl Fischer) | <=0.5 |
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Fmoc-Thr(tBu)-OH
Fmoc-Thr(tBu)-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a building block for introducing threonine residues into peptides while protecting the hydroxyl group with a tert-butyl (tBu) group. The Fmoc (9-fluorenylmethoxycarbonyl) group provides temporary protection for the amino group, allowing for selective deprotection during the synthesis process. This compound is essential in the production of complex peptides and proteins for research, pharmaceuticals, and biotechnology applications. Its stability and compatibility with Fmoc-based synthesis protocols make it a valuable tool in the development of therapeutic peptides, vaccines, and diagnostic agents.
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