Boc-L-pyroglutamic acid dicyclohexylammonium salt
98%
Reagent
Code: #152630
CAS Number
4677-75-2
blur_circular Chemical Specifications
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Molecular Information
Weight
410.55 g/mol
Formula
C₁₀H₁₅NO₅·C₁₂H₂₃N
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Storage & Handling
Storage
Room temperature
description Product Description
Used in peptide synthesis as a protected intermediate, particularly in the preparation of complex peptides where the pyroglutamic acid residue is required at the N-terminus. The Boc (tert-butoxycarbonyl) group provides temporary protection of the alpha-amino function, while the dicyclohexylammonium salt enhances crystallinity and solubility in organic solvents, facilitating purification and handling. Commonly employed in solid-phase and solution-phase peptide coupling strategies. Also useful in the synthesis of pharmaceuticals and bioactive peptides that contain pyroglutamate, such as gonadotropin-releasing hormone (GnRH) analogs and other regulatory peptides.
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