Used in peptide synthesis as a protected amino acid derivative, enabling selective iodination for radiolabeling or cross-coupling reactions in pharmaceutical development. The Boc group provides temporary protection of the amine functionality, allowing controlled stepwise assembly of complex peptides. The iodine atom serves as a handle for further modification via palladium-catalyzed reactions such as Suzuki or Heck couplings, making it valuable in the design of bioactive molecules and targeted therapeutics. Commonly applied in the synthesis of enzyme inhibitors and receptor ligands where precise stereochemistry and functionalization are critical.